These connected domains describe the journal's principal scientific coverage. Work may span more than one domain; the examples are illustrative, not an exhaustive list of permitted topics.
Organic and synthetic chemistry
Organic reactions, synthetic methodology, reagents, stereochemistry, homogeneous and heterogeneous catalysis, natural-product synthesis, and nucleoside, carbohydrate and heterocyclic chemistry. Preparative routes and reaction development belong here when they make a substantive chemical contribution.
Inorganic and coordination chemistry
Main-group, transition-metal, organometallic, coordination, cluster and bioinorganic chemistry, including synthesis, bonding, speciation and reactivity. Metal–ligand interactions, catalyst design and chemically defined self-assembly are included.
Physical chemistry and spectroscopy
Thermodynamics, equilibria, kinetics, reaction mechanisms, electrochemistry, photochemistry and chemical dynamics. Spectroscopy and chemical physics may address molecular interactions, electronic structure, excited states, surfaces and interfaces.
Analytical chemistry and measurement science
Separation science, chromatography, mass spectrometry, spectroscopy, electroanalysis, chemical sensors and biosensors. Method development, validation, uncertainty, reference methods and bioanalytical or pharmaceutical measurements are considered when the analytical contribution is substantive.
Materials, polymer and nanochemistry
Synthesis, composition and chemical characterization of functional solids, polymers, nanomaterials, porous frameworks, composites and biomaterials. Studies may establish structure–property relationships, chemical stability, surface functionalization or interfacial behavior.
Computational and theoretical chemistry
Quantum chemistry, electronic-structure theory, molecular simulation, statistical mechanics, chemoinformatics and data-driven chemical methods. Predictions, models and algorithms should address a chemical question and include verification or validation suited to their claims.
Medicinal chemistry and chemical biology
Medicinal and pharmaceutical chemistry, bioorganic chemistry, molecular biochemistry, molecular design and synthesis, structure–activity relationships, chemical probes, enzyme chemistry and biomolecular interactions. Biological evaluation, including antiproliferative testing, may support chemical advances; molecular toxicology, metabolite identification and biotransformation chemistry are also within this remit.
Energy, environment and sustainable chemistry
Energy conversion and storage, hydrogen chemistry, electrocatalysis, corrosion, atmospheric and aquatic chemistry, pollutant fate and remediation. Green synthesis, renewable feedstocks, biomass conversion and resource recovery fit when chemical processes, measurements or materials are central.