Research Topic · Peer-Reviewed

Pathology of Colorectal Cancer

The pathology of colorectal cancer is the study of how cancers of the colon and rectum arise, develop, and spread at the level of cells and tissues. Most colorectal cancers begin as benign growths in the lining of the bowel, such as adenomatous or serrated polyps, that can progressively acquire genetic and molecular…

Curated from this journal's research 📚 9 peer-reviewed articles cited Cited 30× across the literature 🔖 ISSN 2471-7061 🗓 Reviewed July 2026

Overview

The pathology of colorectal cancer is the study of how cancers of the colon and rectum arise, develop, and spread at the level of cells and tissues. Most colorectal cancers begin as benign growths in the lining of the bowel, such as adenomatous or serrated polyps, that can progressively acquire genetic and molecular changes and transform into invasive carcinoma over time through recognized pathways of carcinogenesis. Pathologists examine tissue samples to determine the tumor type, grade, depth of invasion, and stage, and to assess molecular features that inform prognosis and treatment. Understanding these processes is central to early detection, accurate diagnosis, prediction of behavior, and the design of effective therapies, as well as to screening programs aimed at identifying precancerous lesions before they progress. Research within Colon And Rectal Cancer relevant to this topic includes work on serrated lesions of the colorectum as a distinct pathway in colorectal carcinogenesis, which examines a route to malignancy beyond the classical adenoma sequence, alongside studies addressing diagnostic and screening approaches such as molecular quantification of microRNAs for colon cancer detection. These reflect the field's focus on the cellular and molecular basis of disease. This page gathers peer-reviewed, open-access research relevant to the pathology of colorectal cancer and colorectal carcinogenesis.

Research published in this journal

9 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 9 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Pathology of Colorectal Cancer, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Colon And Rectal Cancer (ISSN 2471-7061).

Journal editorial board
Frank A. Frizelle · New Zealand Gennaro Galizia · Italy Tamotsu Tsukahara · Japan

This page summarises published research for orientation; it is not medical or professional advice.